Units from United Fire Company Station's 3 and 31 along with Urbana Fire Company and Frederick County ALS were dispatched for a reported vehicle collision with entrapment. Battalion 901 was the first arriving unit confirming vehicle on it's side with a subject still in the vehicle I-270 south bound just south of the Monocacy River. Chief 3-1 arriving on the scene along with Company 31 units and establishing command, confirming subject trapped in the vehicle, requiring extrication. State Highway Administration controlled traffic. Rescue Squad 3 and E-231 arriving on the scene beginning vehicle stabilization. Crews utilizing hydraulic cutters and spreaders along with the battery operated sawzall to perform a roof flap of the vehicle. Subject removed from the vehicle to be assessed by Urbana's Ambulance and Medic 31. Subject transported to Frederick Memorial Hospital under ALS care. Command terminated, units clearing as ready. Scene released to Maryland State Police and State Highway Administration.